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Methods Overview For the present study, we used a meta-analytic tool, MR-BRT (metaregressionBayesian, regularized, trimmed), to estimate the doseresponse risk curves of the risk of a health outcome across the range of current smoking levels along with uncertainty estimates 28

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the young group, middle-age group, and old-age group when compared to their respective control groups (YC=31.57%, YS=24.04%, MC=26.81%, MS=19.33%, OC=16.32%, OS=10.84%) (Figure 1)

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